September 23, 2026 at 2:07 AM

After-Hours Movers: JAGX, IPDN Lead Tuesday's Small-Cap Gainers

Eight small-cap names posted notable extended-hours moves on September 22, 2026, with fresh healthcare headlines surfacing alongside the session's biggest gainers.

After-hours movers roundup

SmallCapsDaily's after-hours scan for Tuesday, September 22, 2026, flagged eight small-cap stocks posting outsized extended-hours moves as of 4:45 p.m. ET. The full market table with prices, percentage changes, volume, and market capitalization appears above.

Below is a quick editorial read on each name, summarizing the reported headlines that surfaced alongside the move. Where a headline is dated well before the session, or appears to reference a different issuer, that context is noted; none of these items confirm causality for the price action.

Top 8 After-Hours Movers

Scanner snapshot captured 2026-09-22T20:45:02.591Z.

#TickerCompanyMovePriceVolumeMarket Cap
1JAGXJaguar Health, Inc.+75.4%$60.451,104,405$919,957
2IPDNProfessional Diversity Network, Inc.+63.8%$6.393,907,990$2.6M
3TLSITriSalus Life Sciences, Inc.+23.1%$6.07817,359$303.6M
4BJDXBluejay Diagnostics, Inc.+19.0%$1.191,057,203$4.5M
5MSSMaison Solutions Inc.+14.1%$1.78933,924$1.3M
6SOSSOS Limited+11.2%$0.3877189,783$14.1M
7CDTCDT Equity Inc.+6.5%$0.15151,075,189$1.9M
8DCOYDecoy Therapeutics Inc.+5.8%$3.28237,561$2.0M

What’s Driving the Moves

JAGX — Jaguar Health, Inc.

Jaguar Health topped the after-hours scan. A possible catalyst surfaced earlier Tuesday in a report headlined "Jaguar Health Receives Fee Waivers from FDA", published September 22, 2026.

The headline indicates the company received fee waivers from the FDA; no further terms were detailed in the headline itself, and it remains a reported — not confirmed — driver of the extended-hours move.

IPDN — Professional Diversity Network, Inc.

Professional Diversity Network posted the scan's second-largest extended-hours gain. The most recent surfaced headline, "Professional Diversity Network Launches PDN Intelligence to Advance GPU-Powered AI Infrastructure", is dated August 21, 2026.

Given the gap between that publication date and Tuesday's session, the launch announcement should be treated only as a possible contributing narrative rather than a confirmed catalyst for the move.

TLSI — TriSalus Life Sciences, Inc.

TriSalus Life Sciences ranked third in the scan. A headline published September 22, 2026, shortly before the scan timestamp, reported "TriSalus Life Sciences Receives FDA Clearance for TriNav® Advance, Strengthening Comprehensive Pressure-Enabled Drug Delivery™ (PEDD™) Portfolio for Liver Embolization".

The timing of the reported clearance makes it a plausible contributor to the extended-hours activity, though the linkage remains unconfirmed.

BJDX — Bluejay Diagnostics, Inc.

Bluejay Diagnostics moved higher in the extended session. The surfaced headline, "Bluejay Diagnostics Federal Healthcare Partnership Builds Commercial Pathway Ahead of FDA Clearance", is dated September 8, 2026.

Because the reported partnership news predates Tuesday's session by two weeks, it can only be framed as a possible background catalyst rather than a session-specific driver.

MSS — Maison Solutions Inc.

Maison Solutions appeared mid-table in the after-hours scan. The surfaced headline, dated August 26, 2026, reported "Maison Solutions Eliminates All Outstanding Convertible Notes, Removing Legacy Financing Overhang".

The reported balance-sheet development is several weeks old and is presented only as a possible contributor to sentiment around the name, not as a confirmed cause of Tuesday's move.

SOS — SOS Limited

SOS Limited registered a double-digit extended-hours gain in the scan. The only surfaced headline, "Why Sosandar Plc (LON:SOS) Could Be Worth Watching", dated April 15, 2026, references Sosandar Plc, a London-listed issuer sharing the SOS ticker, rather than SOS Limited.

On that basis, the headline should not be read as a catalyst for SOS Limited. No company-specific catalyst was confirmed as of this scan.

CDT — CDT Equity Inc.

CDT Equity posted a more moderate extended-hours gain relative to the names above it in the scan. A headline dated September 18, 2026, reported "CDT Partners with QIMA Life Sciences to Evaluate Novel Tapinarof Combinations in Psoriasis and Vitiligo".

The reported collaboration is a possible catalyst for recent interest in the stock, though it was published days before Tuesday's session and no causal link to the after-hours move has been confirmed.

DCOY — Decoy Therapeutics Inc.

Decoy Therapeutics rounded out the scan. A headline published September 22, 2026, reported "Decoy Therapeutics Exploring Pan-Filovirus Program via FDA Animal Rule Pathway and Non-Dilutive Funding".

The same-day publication timing makes the reported program exploration a possible catalyst for the extended-hours activity, though the connection remains unconfirmed.

What To Watch Next

Heading into Wednesday's regular session, traders will be watching whether the extended-hours gains hold once full liquidity returns, and whether any of the reported headlines are followed by formal company statements, filings, or additional detail. Names whose surfaced headlines are dated well before the session — or, in the case of SOS, appear to reference a different issuer — may warrant extra caution before attributing the move to company-specific news.

Extended-hours trading carries wider spreads and thinner volume than the regular session, and reported catalysts remain unconfirmed drivers until corroborated. Readers should verify headlines directly with the linked sources and company disclosures before making any trading decision.